Max Planck Institute for Molecular Genetics - Ihnestraße 63-73 - 14195 Berlin - Germany - Phone: (+49 30) 8413 0 - Fax: (+49 30) 8413 1394
  Max Planck Institute for Molecular Genetics - Ihnestraße 63-73 - 14195 Berlin - Germany - Phone: (+49 30) 8413 0 -
Fax: (+49 30) 8413 1394 -

Chromosome 21, Gene Expression and Regulation

Chromosome 21


and other resources

and supplementary information


[external link] Links


Supplementary information to the manuscript:

A gene expression map of human chromosome 21 orthologues in the mouse

The HSA21 expression map initiative
*Group 1: Yorick Gitton, Nadia Dahmane, Sonya Baik1, Ariel Ruiz i Altaba1
*Group 2: Lorenz Neidhardt, Manuela Scholze2, Bernhard G. Herrmann2
*Group 3: Pascal Kahlem, Alia BenKahla, Sabine Schrinner3, Reha Yildirimman3, Ralf Herwig3, Hans Lehrach3, Marie-Laure Yaspo3
* The three groups contributed equally to the work
§ The authors contributed equally

Affiliations for Authors:
- Group 1: Skirball Institute, Developmental Genetics Program and Dept. of Cell Biology, NYU School of Medicine, 540 First Avenue, NY, NY 10016, USA. Université de la Méditerannée-CNRS, Institut de Biologie du Développement, Campus de Luminy, Case 907, 13 288 Marseille Cedex 09, France.
- Group 2: Max-Planck-Institute for Immunology, Dept. of Developmental Biology, Stübeweg 51, D-79108 Freiburg, Germany.
- Group 3: Max-Planck-Institute for Molecular Genetics, Dept. of Vertebrate Genomics, Ihnestrasse 73, D-14195 Berlin, Germany.

Supplementary Information:
Table 1: expression map of chr.21 orthologues in the mouse
Go to HSA21 Database
Supplementary Material and Methods:
Material and Methods(PDF file)
Sequences of oligonucleotide primers used for RT-PCR studies and for mapping the mmu21 genes on mouse chromosomes. Primers are given with reference to clone numbers and gene names. For mapping, in silico information is also indicated together with synteny between HSA21 and MMU16, 10 and 17 (mmu21 primers mapping (PDF file))
Figure 4: Browser allowing to navigate in the matrix presented in Figure 4 and providing access to gene names and EST library descriptions displayed in the bottom line (WARNING: Visualising this image is only optimal on a UNIX workstation)
Figure 4: Dendograms (UPGMA trees) of the 159 mmu21 genes and of the 190 EST libraries, respectively, used to re-arrange the expression matrix shown in Fig. 4
Figure 4: Description of the 190 EST libraries represented in Figure 4, indicating their size, tissue origin and their reference UNILIB numbers in the EMBL database
List and description of the EST libraries used for the comparison of the ISH and WISH data with the EST mining


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